diff --git a/.gitignore b/.gitignore
new file mode 100644
index 0000000..a021fa0
--- /dev/null
+++ b/.gitignore
@@ -0,0 +1,52 @@
+# Ignore EMACS flycheck and Tex files
+
+__latexindent_temp.tex
+.DS_Store
+
+*~
+\#*\#
+/.emacs.desktop
+/.emacs.desktop.lock
+*.elc
+auto-save-list
+tramp
+.\#*
+
+# Org-mode
+.org-id-locations
+*_archive
+
+# flymake-mode
+*_flymake.*
+
+# eshell files
+/eshell/history
+/eshell/lastdir
+
+# elpa packages
+/elpa/
+
+# reftex files
+*.rel
+
+# AUCTeX auto folder
+/auto/
+
+# cask packages
+.cask/
+dist/
+
+# Flycheck
+flycheck_*.el
+
+# server auth directory
+/server/
+
+# projectiles files
+.projectile
+
+# directory configuration
+.dir-locals.el
+
+# network security
+/network-security.data
\ No newline at end of file
diff --git a/Assemblies of putative SARS-CoV2-spike-encoding mRNA sequences for vaccines BNT-162b2 and mRNA-1273.docx.pdf b/Assemblies of putative SARS-CoV2-spike-encoding mRNA sequences for vaccines BNT-162b2 and mRNA-1273.docx.pdf
deleted file mode 100644
index 01c6421..0000000
Binary files a/Assemblies of putative SARS-CoV2-spike-encoding mRNA sequences for vaccines BNT-162b2 and mRNA-1273.docx.pdf and /dev/null differ
diff --git a/Makefile b/Makefile
new file mode 100644
index 0000000..3ed84d5
--- /dev/null
+++ b/Makefile
@@ -0,0 +1,16 @@
+all: sequenced.pdf sequenced.docx sequenced.txt sequenced.html
+
+sequenced.html: sequenced.md style.css
+	pandoc --standalone -c style.css --from markdown --to html5 -o sequenced.html sequenced.md
+
+sequenced.pdf: sequenced.html
+	wkhtmltopdf --enable-local-file-access sequenced.html sequenced.pdf
+
+sequenced.docx: sequenced.md
+	pandoc --from markdown --to docx -o sequenced.docx sequenced.md
+
+sequenced.txt: sequenced.md
+	pandoc --standalone --from markdown-smart --to plain -o sequenced.txt sequenced.md
+
+clean:
+	rm -f *.html *.pdf *.docx *.txt