mirror of
https://github.com/NAalytics/Assemblies-of-putative-SARS-CoV2-spike-encoding-mRNA-sequences-for-vaccines-BNT-162b2-and-mRNA-1273.git
synced 2024-06-18 02:24:03 +00:00
355f94eafc
* Cleaned up and fixed the raw text files (some features such as the start codon were misplaced) * Fixed moderna.gb (it had the BioNTech/Pfizer sequence) * Added BioNTech/Pfizer Genbank file and FASTA files for both vaccines
117 lines
7.8 KiB
Plaintext
117 lines
7.8 KiB
Plaintext
LOCUS 4004 bp RNA linear SYN 23-MAR-2021
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DEFINITION Moderna mRNA-1273 vaccine, spike-encoding contig
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SOURCE synthetic construct
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ORGANISM synthetic construct
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other sequences; artificial sequences.
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REFERENCE 1 (bases 1 to 8179)
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AUTHORS Jeong DE, McCoy M, Artiles K, Ilbay O, Fire A, Nadeau K, Park H,
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Betts B, Boyd S, Hoh R, and Shoura M
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TITLE Assemblies of putative SARS-CoV2-spike-encoding mRNA sequences for
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vaccines BNT-162b2 and mRNA-1273. (version 0.1Beta 03/23/21)
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FEATURES Location/Qualifiers
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source 1..4004
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/organism="synthetic construct"
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/mol_type="other RNA"
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gene 1..4004
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/gene="spike glycoprotein"
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/db_xref="GeneID:43740568"
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5'UTR 1..57
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CDS 58..3879
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/codon_start=1
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/product="spike glycoprotein"
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/translation="MFVFLVLLPLVSSQCVNLTTRTQLPPAYTNSFTRGVYYPDKVFR
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SSVLHSTQDLFLPFFSNVTWFHAIHVSGTNGTKRFDNPVLPFNDGVYFASTEKSNIIR
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GWIFGTTLDSKTQSLLIVNNATNVVIKVCEFQFCNDPFLGVYYHKNNKSWMESEFRVY
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SSANNCTFEYVSQPFLMDLEGKQGNFKNLREFVFKNIDGYFKIYSKHTPINLVRDLPQ
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GFSALEPLVDLPIGINITRFQTLLALHRSYLTPGDSSSGWTAGAAAYYVGYLQPRTFL
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LKYNENGTITDAVDCALDPLSETKCTLKSFTVEKGIYQTSNFRVQPTESIVRFPNITN
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LCPFGEVFNATRFASVYAWNRKRISNCVADYSVLYNSASFSTFKCYGVSPTKLNDLCF
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TNVYADSFVIRGDEVRQIAPGQTGKIADYNYKLPDDFTGCVIAWNSNNLDSKVGGNYN
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YLYRLFRKSNLKPFERDISTEIYQAGSTPCNGVEGFNCYFPLQSYGFQPTNGVGYQPY
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RVVVLSFELLHAPATVCGPKKSTNLVKNKCVNFNFNGLTGTGVLTESNKKFLPFQQFG
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RDIADTTDAVRDPQTLEILDITPCSFGGVSVITPGTNTSNQVAVLYQDVNCTEVPVAI
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HADQLTPTWRVYSTGSNVFQTRAGCLIGAEHVNNSYECDIPIGAGICASYQTQTNSPR
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RARSVASQSIIAYTMSLGAENSVAYSNNSIAIPTNFTISVTTEILPVSMTKTSVDCTM
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YICGDSTECSNLLLQYGSFCTQLNRALTGIAVEQDKNTQEVFAQVKQIYKTPPIKDFG
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GFNFSQILPDPSKPSKRSFIEDLLFNKVTLADAGFIKQYGDCLGDIAARDLICAQKFN
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GLTVLPPLLTDEMIAQYTSALLAGTITSGWTFGAGAALQIPFAMQMAYRFNGIGVTQN
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VLYENQKLIANQFNSAIGKIQDSLSSTASALGKLQDVVNQNAQALNTLVKQLSSNFGA
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ISSVLNDILSRLDPPEAEVQIDRLITGRLQSLQTYVTQQLIRAAEIRASANLAATKMS
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ECVLGQSKRVDFCGKGYHLMSFPQSAPHGVVFLHVTYVPAQEKNFTTAPAICHDGKAH
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FPREGVFVSNGTHWFVTQRNFYEPQIITTDNTFVSGNCDVVIGIVNNTVYDPLQPELD
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SFKEELDKYFKNHTSPDVDLGDISGINASVVNIQKEIDRLNEVAKNLNESLIDLQELG
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KYEQYIKWPWYIWLGFIAGLIAIVMVTIMLCCMTSCCSCLKGCCSCGSCCKFDEDDSE
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PVLKGVKLHYT"
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3'UTR 3880..3995
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polyA_signal 3996..4004
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ORIGIN
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1 gggaaataag agagaaaaga agagtaagaa gaaatataag accccggcgc cgccaccatg
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61 ttcgtgttcc tggtgctgct gcccctggtg agcagccagt gcgtgaacct gaccacccgg
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121 acccagctgc caccagccta caccaacagc ttcacccggg gcgtctacta ccccgacaag
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181 gtgttccgga gcagcgtcct gcacagcacc caggacctgt tcctgccctt cttcagcaac
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241 gtgacctggt tccacgccat ccacgtgagc ggcaccaacg gcaccaagcg gttcgacaac
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301 cccgtgctgc ccttcaacga cggcgtgtac ttcgccagca ccgagaagag caacatcatc
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361 cggggctgga tcttcggcac caccctggac agcaagaccc agagcctgct gatcgtgaat
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421 aacgccacca acgtggtgat caaggtgtgc gagttccagt tctgcaacga ccccttcctg
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481 ggcgtgtact accacaagaa caacaagagc tggatggaga gcgagttccg ggtgtacagc
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541 agcgccaaca actgcacctt cgagtacgtg agccagccct tcctgatgga cctggagggc
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601 aagcagggca acttcaagaa cctgcgggag ttcgtgttca agaacatcga cggctacttc
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661 aagatctaca gcaagcacac cccaatcaac ctggtgcggg atctgcccca gggcttctca
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721 gccctggagc ccctggtgga cctgcccatc ggcatcaaca tcacccggtt ccagaccctg
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781 ctggccctgc accggagcta cctgacccca ggcgacagca gcagcgggtg gacagcaggc
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841 gcggctgctt actacgtggg ctacctgcag ccccggacct tcctgctgaa gtacaacgag
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901 aacggcacca tcaccgacgc cgtggactgc gccctggacc ctctgagcga gaccaagtgc
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961 accctgaaga gcttcaccgt ggagaagggc atctaccaga ccagcaactt ccgggtgcag
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1021 cccaccgaga gcatcgtgcg gttccccaac atcaccaacc tgtgcccctt cggcgaggtg
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1081 ttcaacgcca cccggttcgc cagcgtgtac gcctggaacc ggaagcggat cagcaactgc
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1141 gtggccgact acagcgtgct gtacaacagc gccagcttca gcaccttcaa gtgctacggc
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1201 gtgagcccca ccaagctgaa cgacctgtgc ttcaccaacg tgtacgccga cagcttcgtg
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1261 atccgtggcg acgaggtgcg gcagatcgca cccggccaga caggcaagat cgccgactac
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1321 aactacaagc tgcccgacga cttcaccggc tgcgtgatcg cctggaacag caacaacctc
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1381 gacagcaagg tgggcggcaa ctacaactac ctgtaccggc tgttccggaa gagcaacctg
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1441 aagcccttcg agcgggacat cagcaccgag atctaccaag ccggctccac cccttgcaac
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1501 ggcgtggagg gcttcaactg ctacttccct ctgcagagct acggcttcca gcccaccaac
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1561 ggcgtgggct accagcccta ccgggtggtg gtgctgagct tcgagctgct gcacgcccca
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1621 gccaccgtgt gtggccccaa gaagagcacc aacctggtga agaacaagtg cgtgaacttc
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1681 aacttcaacg gccttaccgg caccggcgtg ctgaccgaga gcaacaagaa attcctgccc
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1741 tttcagcagt tcggccggga catcgccgac accaccgacg ctgtgcggga tccccagacc
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1801 ctggagatcc tggacatcac cccttgcagc ttcggcggcg tgagcgtgat caccccaggc
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1861 accaacacca gcaaccaggt ggccgtgctg taccaggacg tgaactgcac cgaggtgccc
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1921 gtggccatcc acgccgacca gctgacaccc acctggcggg tctacagcac cggcagcaac
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1981 gtgttccaga cccgggccgg ttgcctgatc ggcgccgagc acgtgaacaa cagctacgag
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2041 tgcgacatcc ccatcggcgc cggcatctgt gccagctacc agacccagac caattcaccc
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2101 cggagggcaa ggagcgtggc cagccagagc atcatcgcct acaccatgag cctgggcgcc
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2161 gagaacagcg tggcctacag caacaacagc atcgccatcc ccaccaactt caccatcagc
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2221 gtgaccaccg agattctgcc cgtgagcatg accaagacca gcgtggactg caccatgtac
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2281 atctgcggcg acagcaccga gtgcagcaac ctgctgctgc agtacggcag cttctgcacc
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2341 cagctgaacc gggccctgac cggcatcgcc gtggagcagg acaagaacac ccaggaggtg
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2401 ttcgcccagg tgaagcagat ctacaagacc cctcccatca aggacttcgg cggcttcaac
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2461 ttcagccaga tcctgcccga ccccagcaag cccagcaagc ggagcttcat cgaggacctg
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2521 ctgttcaaca aggtgaccct agccgacgcc ggcttcatca agcagtacgg cgactgcctc
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2581 ggcgacatag ccgcccggga cctgatctgc gcccagaagt tcaacggcct gaccgtgctg
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2641 cctcccctgc tgaccgacga gatgatcgcc cagtacacca gcgccctgtt agccggaacc
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2701 atcaccagcg gctggacttt cggcgctgga gccgctctgc agatcccctt cgccatgcag
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2761 atggcctacc ggttcaacgg catcggcgtg acccagaacg tgctgtacga gaaccagaag
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2821 ctgatcgcca accagttcaa cagcgccatc ggcaagatcc aggacagcct gagcagcacc
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2881 gctagcgccc tgggcaagct gcaggacgtg gtgaaccaga acgcccaggc cctgaacacc
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2941 ctggtgaagc agctgagcag caacttcggc gccatcagca gcgtgctgaa cgacatcctg
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3001 agccggctgg accctcccga ggccgaggtg cagatcgacc ggctgatcac tggccggctg
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3061 cagagcctgc agacctacgt gacccagcag ctgatccggg ccgccgagat tcgggccagc
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3121 gccaacctgg ccgccaccaa gatgagcgag tgcgtgctgg gccagagcaa gcgggtggac
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3181 ttctgcggca agggctacca cctgatgagc tttccccaga gcgcacccca cggagtggtg
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3241 ttcctgcacg tgacctacgt gcccgcccag gagaagaact tcaccaccgc cccagccatc
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3301 tgccacgacg gcaaggccca ctttccccgg gagggcgtgt tcgtgagcaa cggcacccac
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3361 tggttcgtga cccagcggaa cttctacgag ccccagatca tcaccaccga caacaccttc
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3421 gtgagcggca actgcgacgt ggtgatcggc atcgtgaaca acaccgtgta cgatcccctg
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3481 cagcccgagc tggacagctt caaggaggag ctggacaagt acttcaagaa tcacaccagc
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3541 cccgacgtgg acctgggcga catcagcggc atcaacgcca gcgtggtgaa catccagaag
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3601 gagatcgatc ggctgaacga ggtggccaag aacctgaacg agagcctgat cgacctgcag
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3661 gagctgggca agtacgagca gtacatcaag tggccctggt acatctggct gggcttcatc
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3721 gccggcctga tcgccatcgt gatggtgacc atcatgctgt gctgcatgac cagctgctgc
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3781 agctgcctga agggctgttg cagctgcggc agctgctgca agttcgacga ggacgacagc
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3841 gagcccgtgc tgaagggcgt gaagctgcac tacacctgat aataggctgg agcctcggtg
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3901 gcctagcttc ttgccccttg ggcctccccc cagcccctcc tccccttcct gcacccgtac
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3961 ccccgtggtc tttgaataaa gtctgagtgg gcggcaaaaa aaaa
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//
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