mirror of
https://github.com/NAalytics/Assemblies-of-putative-SARS-CoV2-spike-encoding-mRNA-sequences-for-vaccines-BNT-162b2-and-mRNA-1273.git
synced 2024-06-29 07:29:01 +00:00
355f94eafc
* Cleaned up and fixed the raw text files (some features such as the start codon were misplaced) * Fixed moderna.gb (it had the BioNTech/Pfizer sequence) * Added BioNTech/Pfizer Genbank file and FASTA files for both vaccines
120 lines
8.0 KiB
Plaintext
120 lines
8.0 KiB
Plaintext
LOCUS 4175 bp RNA linear SYN 23-MAR-2021
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DEFINITION BioNTech/Pfizer BNT-162b2 vaccine, spike-encoding contig
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SOURCE synthetic construct
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ORGANISM synthetic construct
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other sequences; artificial sequences.
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REFERENCE 1 (bases 1 to 8179)
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AUTHORS Jeong DE, McCoy M, Artiles K, Ilbay O, Fire A, Nadeau K, Park H,
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Betts B, Boyd S, Hoh R, and Shoura M
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TITLE Assemblies of putative SARS-CoV2-spike-encoding mRNA sequences for
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vaccines BNT-162b2 and mRNA-1273. (version 0.1Beta 03/23/21)
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FEATURES Location/Qualifiers
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source 1..4175
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/organism="synthetic construct"
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/mol_type="other RNA"
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gene 1..4175
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/gene="spike glycoprotein"
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/db_xref="GeneID:43740568"
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5'UTR 1..54
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CDS 55..3876
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/codon_start=1
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/product="spike glycoprotein"
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/translation="MFVFLVLLPLVSSQCVNLTTRTQLPPAYTNSFTRGVYYPDKVFR
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SSVLHSTQDLFLPFFSNVTWFHAIHVSGTNGTKRFDNPVLPFNDGVYFASTEKSNIIR
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GWIFGTTLDSKTQSLLIVNNATNVVIKVCEFQFCNDPFLGVYYHKNNKSWMESEFRVY
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SSANNCTFEYVSQPFLMDLEGKQGNFKNLREFVFKNIDGYFKIYSKHTPINLVRDLPQ
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GFSALEPLVDLPIGINITRFQTLLALHRSYLTPGDSSSGWTAGAAAYYVGYLQPRTFL
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LKYNENGTITDAVDCALDPLSETKCTLKSFTVEKGIYQTSNFRVQPTESIVRFPNITN
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LCPFGEVFNATRFASVYAWNRKRISNCVADYSVLYNSASFSTFKCYGVSPTKLNDLCF
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TNVYADSFVIRGDEVRQIAPGQTGKIADYNYKLPDDFTGCVIAWNSNNLDSKVGGNYN
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YLYRLFRKSNLKPFERDISTEIYQAGSTPCNGVEGFNCYFPLQSYGFQPTNGVGYQPY
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RVVVLSFELLHAPATVCGPKKSTNLVKNKCVNFNFNGLTGTGVLTESNKKFLPFQQFG
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RDIADTTDAVRDPQTLEILDITPCSFGGVSVITPGTNTSNQVAVLYQDVNCTEVPVAI
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HADQLTPTWRVYSTGSNVFQTRAGCLIGAEHVNNSYECDIPIGAGICASYQTQTNSPR
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RARSVASQSIIAYTMSLGAENSVAYSNNSIAIPTNFTISVTTEILPVSMTKTSVDCTM
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YICGDSTECSNLLLQYGSFCTQLNRALTGIAVEQDKNTQEVFAQVKQIYKTPPIKDFG
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GFNFSQILPDPSKPSKRSFIEDLLFNKVTLADAGFIKQYGDCLGDIAARDLICAQKFN
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GLTVLPPLLTDEMIAQYTSALLAGTITSGWTFGAGAALQIPFAMQMAYRFNGIGVTQN
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VLYENQKLIANQFNSAIGKIQDSLSSTASALGKLQDVVNQNAQALNTLVKQLSSNFGA
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ISSVLNDILSRLDPPEAEVQIDRLITGRLQSLQTYVTQQLIRAAEIRASANLAATKMS
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ECVLGQSKRVDFCGKGYHLMSFPQSAPHGVVFLHVTYVPAQEKNFTTAPAICHDGKAH
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FPREGVFVSNGTHWFVTQRNFYEPQIITTDNTFVSGNCDVVIGIVNNTVYDPLQPELD
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SFKEELDKYFKNHTSPDVDLGDISGINASVVNIQKEIDRLNEVAKNLNESLIDLQELG
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KYEQYIKWPWYIWLGFIAGLIAIVMVTIMLCCMTSCCSCLKGCCSCGSCCKFDEDDSE
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PVLKGVKLHYT"
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3'UTR 3877..4174
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polyA_signal 4174..4175
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ORIGIN
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1 gagaataaac tagtattctt ctggtcccca cagactcaga gagaacccgc caccatgttc
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61 gtgttcctgg tgctgctgcc tctggtgtcc agccagtgtg tgaacctgac caccagaaca
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121 cagctgcctc cagcctacac caacagcttt accagaggcg tgtactaccc cgacaaggtg
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181 ttcagatcca gcgtgctgca ctctacccag gacctgttcc tgcctttctt cagcaacgtg
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241 acctggttcc acgccatcca cgtgtccggc accaatggca ccaagagatt cgacaacccc
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301 gtgctgccct tcaacgacgg ggtgtacttt gccagcaccg agaagtccaa catcatcaga
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361 ggctggatct tcggcaccac actggacagc aagacccaga gcctgctgat cgtgaacaac
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421 gccaccaacg tggtcatcaa agtgtgcgag ttccagttct gcaacgaccc cttcctgggc
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481 gtctactacc acaagaacaa caagagctgg atggaaagcg agttccgggt gtacagcagc
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541 gccaacaact gcaccttcga gtacgtgtcc cagcctttcc tgatggacct ggaaggcaag
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601 cagggcaact tcaagaacct gcgcgagttc gtgtttaaga acatcgacgg ctacttcaag
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661 atctacagca agcacacccc tatcaacctc gtgcgggatc tgcctcaggg cttctctgct
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721 ctggaacccc tggtggatct gcccatcggc atcaacatca cccggtttca gacactgctg
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781 gccctgcaca gaagctacct gacacctggc gatagcagca gcggatggac agctggtgcc
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841 gccgcttact atgtgggcta cctgcagcct agaaccttcc tgctgaagta caacgagaac
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901 ggcaccatca ccgacgccgt ggattgtgct ctggatcctc tgagcgagac aaagtgcacc
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961 ctgaagtcct tcaccgtgga aaagggcatc taccagacca gcaacttccg ggtgcagccc
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1021 accgaatcca tcgtgcggtt ccccaatatc accaatctgt gccccttcgg cgaggtgttc
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1081 aatgccacca gattcgcctc tgtgtacgcc tggaaccgga agcggatcag caattgcgtg
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1141 gccgactact ccgtgctgta caactccgcc agcttcagca ccttcaagtg ctacggcgtg
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1201 tcccctacca agctgaacga cctgtgcttc acaaacgtgt acgccgacag cttcgtgatc
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1261 cggggagatg aagtgcggca gattgcccct ggacagacag gcaagatcgc cgactacaac
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1321 tacaagctgc ccgacgactt caccggctgt gtgattgcct ggaacagcaa caacctggac
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1381 tccaaagtcg gcggcaacta caattacctg taccggctgt tccggaagtc caatctgaag
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1441 cccttcgagc gggacatctc caccgagatc tatcaggccg gcagcacccc ttgtaacggc
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1501 gtggaaggct tcaactgcta cttcccactg cagtcctacg gctttcagcc cacaaatggc
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1561 gtgggctatc agccctacag agtggtggtg ctgagcttcg aactgctgca tgcccctgcc
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1621 acagtgtgcg gccctaagaa aagcaccaat ctcgtgaaga acaaatgcgt gaacttcaac
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1681 ttcaacggcc tgaccggcac cggcgtgctg acagagagca acaagaagtt cctgccattc
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1741 cagcagtttg gccgggatat cgccgatacc acagacgccg ttagagatcc ccagacactg
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1801 gaaatcctgg acatcacccc ttgcagcttc ggcggagtgt ctgtgatcac ccctggcacc
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1861 aacaccagca atcaggtggc agtgctgtac caggacgtga actgtaccga agtgcccgtg
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1921 gccattcacg ccgatcagct gacacctaca tggcgggtgt actccaccgg cagcaatgtg
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1981 tttcagacca gagccggctg tctgatcgga gccgagcacg tgaacaatag ctacgagtgc
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2041 gacatcccca tcggcgctgg aatctgcgcc agctaccaga cacagacaaa cagccctcgg
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2101 agagccagaa gcgtggccag ccagagcatc attgcctaca caatgtctct gggcgccgag
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2161 aacagcgtgg cctactccaa caactctatc gctatcccca ccaacttcac catcagcgtg
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2221 accacagaga tcctgcctgt gtccatgacc aagaccagcg tggactgcac catgtacatc
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2281 tgcggcgatt ccaccgagtg ctccaacctg ctgctgcagt acggcagctt ctgcacccag
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2341 ctgaatagag ccctgacagg gatcgccgtg gaacaggaca agaacaccca agaggtgttc
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2401 gcccaagtga agcagatcta caagacccct cctatcaagg acttcggcgg cttcaatttc
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2461 agccagattc tgcccgatcc tagcaagccc agcaagcgga gcttcatcga ggacctgctg
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2521 ttcaacaaag tgacactggc cgacgccggc ttcatcaagc agtatggcga ttgtctgggc
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2581 gacattgccg ccagggatct gatttgcgcc cagaagttta acggactgac agtgctgcct
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2641 cctctgctga ccgatgagat gatcgcccag tacacatctg ccctgctggc cggcacaatc
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2701 acaagcggct ggacatttgg agcaggcgcc gctctgcaga tcccctttgc tatgcagatg
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2761 gcctaccggt tcaacggcat cggagtgacc cagaatgtgc tgtacgagaa ccagaagctg
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2821 atcgccaacc agttcaacag cgccatcggc aagatccagg acagcctgag cagcacagca
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2881 agcgccctgg gaaagctgca ggacgtggtc aaccagaatg cccaggcact gaacaccctg
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2941 gtcaagcagc tgtcctccaa cttcggcgcc atcagctctg tgctgaacga tatcctgagc
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3001 agactggacc ctcctgaggc cgaggtgcag atcgacagac tgatcacagg cagactgcag
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3061 agcctccaga catacgtgac ccagcagctg atcagagccg ccgagattag agcctctgcc
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3121 aatctggccg ccaccaagat gtctgagtgt gtgctgggcc agagcaagag agtggacttt
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3181 tgcggcaagg gctaccacct gatgagcttc cctcagtctg cccctcacgg cgtggtgttt
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3241 ctgcacgtga catatgtgcc cgctcaagag aagaatttca ccaccgctcc agccatctgc
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3301 cacgacggca aagcccactt tcctagagaa ggcgtgttcg tgtccaacgg cacccattgg
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3361 ttcgtgacac agcggaactt ctacgagccc cagatcatca ccaccgacaa caccttcgtg
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3421 tctggcaact gcgacgtcgt gatcggcatt gtgaacaata ccgtgtacga ccctctgcag
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3481 cccgagctgg acagcttcaa agaggaactg gacaagtact ttaagaacca cacaagcccc
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3541 gacgtggacc tgggcgatat cagcggaatc aatgccagcg tcgtgaacat ccagaaagag
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3601 atcgaccggc tgaacgaggt ggccaagaat ctgaacgaga gcctgatcga cctgcaagaa
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3661 ctggggaagt acgagcagta catcaagtgg ccctggtaca tctggctggg ctttatcgcc
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3721 ggactgattg ccatcgtgat ggtcacaatc atgctgtgtt gcatgaccag ctgctgtagc
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3781 tgcctgaagg gctgttgtag ctgtggcagc tgctgcaagt tcgacgagga cgattctgag
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3841 cccgtgctga agggcgtgaa actgcactac acatgatgac tcgagctggt actgcatgca
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3901 cgcaatgcta gctgcccctt tcccgtcctg ggtaccccga gtctcccccg acctcgggtc
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3961 ccaggtatgc tcccacctcc acctgcccca ctcaccacct ctgctagttc cagacacctc
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4021 ccaagcacgc agcaatgcag ctcaaaacgc ttagcctagc cacaccccca cgggaaacag
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4081 cagtgattaa cctttagcaa taaacgaaag tttaactaag ctatactaac cccagggttg
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4141 gtcaatttcg tgccagccac accctggagc tagca
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//
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